hrp0098p2-359 | Late Breaking | ESPE2024

High Frequency of Copy Number Variations as Genetic Causes of Failure to Achieve Catch-Up Growth in Small for Gestational Age Children: A Multicenter Study in Korea

Lee Yena , Jae Kang Min , Rim Jeong Hwal , Young Kim Eun , Noh Eu-seon , young Jin Hye , Byul Kwon Eun , Jin Lee Hye , Seo Young-Jun , Young Kim Nan , Hong Sangkyoon , Hong Il-Tae

Background: Small for gestational age (SGA) children are defined by birth weight and/or length at least 2 standard deviations (S.D) below the population mean for gestational age. Up to 90% of these infants experience catch-up growth within the first two years of life; however, 10-15% fail to do so, remaining short at age 2 (SGA-SS). The etiology of failure to achieve catch-up growth remains largely unknown.Methods: This ...