hrp0095p1-116 | Growth and Syndromes | ESPE2022
Patti Giuseppa
, Malerba Federica
, Scaglione Marco
, Schiavone Maurizio
, Grazia Calevo Maria
, Varotto Carolina
, Casalini Emilio
, Fava Daniela
, Allegri Anna
, Napoli Flavia
, Di Iorgi Natascia
, Maghnie Mohamad
Silver-Russell syndrome (SRS) is a rare heterogeneous syndrome associated with severe prenatal and postnatal growth retardation.Context: There is little information on puberty onset and bone age trend in children with SRS.Study Design and partecipants: Retrospective observational study, including patients with a confirmed diagnosis of SRS divided in 2 molecular groups [ 11p15 loss of methylation, (...