hrp0086p2-p870 | Syndromes: Mechanisms and Management P2 | ESPE2016
Schoch Justine
, Schmidt Tina
, Jung Anna-Maria
, Kastner Michael
, Abdul-Khaliq Hashim
, Gortner Ludwig
, Sester Martina
, Rohrer Tilman
Background: Trisomy 21 is associated with an increased susceptibility to respiratory infections.Objective and hypotheses: For a more detailed characterization of the adaptive immune response, we analyzed the cellular and humoral immunity to specific pathogens in blood samples of 40 children with DownÂ’s syndrome in comparison to 51 age-matched controls.Method: We quantitatively analyzed lymphocyte subpopulations using flow cyto...