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hrp0082p1-d3-55 | Bone (1) | ESPE2014

Increased Osteoclast Activity in Children and Adolescents with Type 1 Diabetes Mellitus Indicated by Higher Levels of Osteoprotegerin and s-RANKL may Predispose to Lower Bone Mass

Tsentidis Charalampos , Gourgiotis Dimitrios , Kossiva Lydia , Doulgeraki Artemis , Marmarinos Antonios , Sdogou Triantafillia , Karavanaki Kyriaki

Background: Several bone metabolic pathways seem to be disrupted in patients with type 1 diabetes mellitus (T1DM), leading to reduced bone mass.Objective and hypotheses: Our aim was to study bone metabolism markers in children and adolescents with T1DM and their correlation with bone mineral density (BMD).Method: We evaluated 40 patients (mean±S.D. age 13.04±3.53 years, mean±S.D. T1DM du...

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Increased Osteoclast Activity in Children and Adolescents with Type 1 Diabetes Mellitus Indicated by Higher Levels of Osteoprotegerin and s-RANKL may Predispose to Lower Bone Mass

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