hrp0098p1-82 | Pituitary, Neuroendocrinology and Puberty 1 | ESPE2024

Comparative Analysis of α-Klotho Levels for the Diagnosis of Central Precocious Puberty (CPP) in Children: A Gender-Specific Study

Noh Eu-Seon , Young Kim Eun , Hee Yi Kyung , Tae Hwang Il

Background: Recent studies suggest an association between the Klotho protein, sex hormones, and insulin-like growth factor-1 (IGF-1). Particularly, considering the intricate interplay among α-Klotho, sex hormones, and IGF-1 during puberty, investigating α-Klotho levels in patients with central precocious puberty (CPP) could provide a deeper understanding of the significance of this protein.Methods: A total of...