hrp0098rfc13.4 | Pituitary, Neuroendocrinology and Puberty 2 | ESPE2024

Investigation of Pituitary Function in Langerhans Cell Histiocytosis: A Comprehensive Analysis of Clinical and Radiological Findings

Koc Cansu , Tugcu Deniz , İrkin Damla , Derya Kardelen Asli , Unuvar Aysegul , Karakas Zeynep , Karaman Serap , Tanyildiz Gulsah , Yildiz Melek , Bas Firdevs , Poyrazoglu Sukran

Introduction: Langerhans cell histiocytosis (LCH) is a rare disease that the clinical presentation can vary from the involvement of a single region to widespread multiorgan involvement. The most common central nervous system infiltration is observed in the hypothalamic-pituitary region, which frequently leads to central diabetes insipidus (CDİ) and occasionally to anterior pituitary hormone deficiencies. There is limited data on endocrinological findings,...