hrp0098p2-238 | Pituitary, Neuroendocrinology and Puberty | ESPE2024

Vaginal Bleeding in a Severely Premature Infant During the Mini-Puberty Period

Korkmaz Vural Meltem , Seyma Eken Emine , Ozkaya Donmez Beyhan , Arı Hasan , Kurnaz Erdal , Keskin Meliksah , Aslı Bala Keziban , Seref Kıvanç , Ucan Berna , Savas Erdeve Senay

Introduction: Mini-puberty is defined as the transient activation of the hypothalamic-pituitary-gonadal (HPG) axis during the first 3-6 months of life. Postnatal HPG activation occurs more robustly and for a longer duration in premature infants compared to term infants. In this report, we present a case of severely premature infant who presented with vaginal bleeding during the mini-puberty period.Case: A 5-month and 12-...