hrp0094p2-422 | Sex differentiation, gonads and gynaecology or sex endocrinology | ESPE2021

17-hydroxylase deficiency and diabetes in a case with 46 XY female

Yildirim Ahmet , Zeytun Hikmet , Albayrak Serpil , Karaoğlan Murat , Keskin Mehmet

A 13-year-old patient was admitted due to delayed puberty. Ovary and uterus had not seen in USG and MRI. On physical examination; body weight: 57 kg (79 P), height 157.7 cm (45P), BMI: 22.9 (83P), TA: 120/80 mmHg. The patient was externally in female appearance and there was no puberty development. Labia minora was seen. The urethral and vaginal openings were in the vestibulum and bilateral gonads could not be palpated in the inguinal canal. Mother and father was cousin. Fathe...

hrp0094p2-144 | Diabetes and insulin | ESPE2021

Is Type 1 Diabetes Mellitus Predictable? Investigation of Predictive Markers n Siblings of Probands with Newly Diagnosed Type 1 Diabetes Mellitus

Albayrak Serpil , Karaoglan Murat , Yıldırım Ahmet , Keskin Mehmet ,

Background/Aim: Type 1 diabetes Mellitus (T1DM) often presents with clear clinical signs after a long-term asymptomatic autoimmune process. This long and silent period has been leading to an increase in awareness day by day in order to prevent and predict the development of the disease. Among the well-known genetic and environmental risk factors, close relatives of the index cases constitute a population that is quite suitable for predicting and preventing the...

hrp0095p1-437 | Diabetes and Insulin | ESPE2022

The Relationship between Visceral Adipose Index and Metabolic Syndrome in Children with Type 1 Diabetes Mellitus

Albayrak Serpil , Karaoglan Murat , Keskin Mehmet , Yıldırım Ahmet

Background/Aim: Prediction of metabolic syndrome (Mets) plays important role in cardiovascular disease risk prevention. Although Mets is relatively common in children with T1DM, diagnosis and prediction are ignored. Visceral Adiposity Index VAI) has been defined as a new cardiometabolic risk marker reflecting abdominal fat distribution and dyslipidemia. The aim of the study is to reveal the relationship between Mets and components of VAI in patients with T1DM....

hrp0095p1-367 | Sex Differentiation, Gonads and Gynaecology, and Sex Endocrinology | ESPE2022

Evaluation of The Relationship Between the Immune and Endocrine System in Children Diagnosed with Polycystic Ovary Syndrome

Uygur Balık Ahmet , Keskin Mehmet , Karaoglan Murat , Keskin Ozlem , Yıldırım Ahmet , Albayrak Serpil

Polycystic ovary syndrome is the most common endocrinological disease in women of reproductive age. Although it is thought that pathologies such as insulin resistance, chronic low-level inflammation and hyperandrogenism are central theme of the disease, the exact pathophysiology of the disease has not been fully understood. This study’s aim is to reveal the relationship between routine endocrinological and immunological markers related to chronic inflammation, and to inv...