hrp0098p2-244 | Pituitary, Neuroendocrinology and Puberty | ESPE2024

Rapidly progressing peripheral precocious puberty due to pineal germ cell tumor in a preschool age boy

Dikaiakou Eirini , Doganis Dimitrios , Magkou Evgenia , Lekka-Emiri Sofia , Sfetsiori Aggelina , Chrysis Dionysios , Markogiannakis George , Gavra Maria , Alexopoulou Aikaterini , Baka Margarita , Sertedaki Amalia , Kanaka-Gantenbein Christina , Vlachopapadopoulou Elpis

Introduction: Intracranial germ cell tumors (GCTs) are rare and likely to present with peripheral precocious puberty (PPP). We report the case of a 5-year-old boy with pineal GCT, in whom, although he presented with advanced peripheral precocious puberty, levels of β-chorionic gonadotropin (β-HCG) were mildly elevated, not diagnostic of GCT, posing a diagnostic dilemma.Methods: A 53/12 year- old boy ...