hrp0098p2-198 | Multisystem Endocrine Disorders | ESPE2024

A Correlation Study Between Iron Overload, Chelation Therapy (ICT), and Metabolic Outcomes in β-Thalassemia Major (β-TDT) Patients

De Sanctis Vincenzo , Soliman CAshraf , Daar Shahina , Campisi Saveria , Tzoulis Ploutarchos

Introduction and Aim: We conducted this correlation study to analyze the impact of iron overload and chelation therapy on metabolic outcomes in 30 β-Thalassemia Major (β-TDT) patients, divided into those with prediabetes (Group A, n = 15) and those maintaining normal glucose tolerance (Group B, n = 15) over 8 years of consistent iron chelation therapy (ICT).Results: A negative correlation betw...

hrp0098p2-199 | Multisystem Endocrine Disorders | ESPE2024

Impact of Iron Chelation Therapy Adherence on Prediabetes Development in Young Adult β-Thalassemia Major Patients: A Comparative Analysis

De Sanctis Vincenzo , Soliman Ashraf , Daar Shahina , Campisi Saveria , Tzoulis Ploutarchos

Introduction: In β-Thalassemia major (β-TDT) the influence of consistent iron chelation therapy on prediabetes development remains uncertain.Objectives: To identify factors associated with prediabetes among β-TDT patients adhering to iron chelation therapy by comparing those who developed prediabetes versus those with normal glucose tolerance.Methods: This retrospect...