hrp0097rfc12.4 | Thyroid | ESPE2023

Polyethylene glycol thyroid stimulating hormone (PEG-TSH) in real-life: a practical tool for solving a biochemical dilemma

Zaitoon Hussein , Shefer Gabi , Segev-Becker Anat , Ayal Ori , Lebenthal Yael , Brener Avivit

Background: The polyethylene glycol (PEG) method, which utilizes the addition of PEG to precipitate immunoglobulin fractions in order to measure free thyroid stimulating hormone (TSH), has been implemented as a tool for investigating incongruities in TSH measurement.Aim of the study: To investigate the practical application of PEG-TSH testing in pediatric scenarios with a discrepancy between elevated TSH and normal free ...

hrp0098p2-319 | Late Breaking | ESPE2024

Sex, age and irisin levels in pediatric type 1 diabetes: a pilot study

Averbuch Shay , Gaiduk Oksana , Yackobovitch-Gavan Michal , Laurian Irina , Dorfman Anna , Shefer Gabi , Brener Avivit , Lebenthal Yael

Background: Irisin is a myokine involved in the browning of adipocytes, regulation of body composition, and enhancement of glycemic control. Additionally, irisin has been suggested to play a role in the signaling mechanisms associated with activation of the hypothalamic-pituitary-gonadal axis and the onset of puberty. Given the reported relationship between irisin levels and glycemic control, as well as the link between body composition and glycemic control, w...