hrp0086p2-p62 | Adrenal P2 | ESPE2016
Shir Wey Pang Gloria
, Rumsby Gill
, Hindmarsh Peter C
, Dattani Mehul T
Background: Patients with congenital adrenal hyperplasia (CAH) are glucocorticoid deficient and require cortisol replacement to maintain homeostasis and prevent adrenal crises. Hydrocortisone dosing needs to be individualized because of variable cortisol clearance rates. Patients are thus prone to be either over or undertreated, both of which compromises final height.Objective and hypotheses: Performing 24-h cortisol profiling serially may allow for more...