hrp0098p3-239 | Sex Differentiation, Gonads and Gynaecology, and Sex Endocrinology | ESPE2024

The influence of the 21-CYP mutation on the development of premature adrenarche in girls of Uzbek nationality

Shorikhsieva Mukhlisa , Muminova Sitora

Aim of the work: to study 21-CYP mutations on the development of premature adrenarche in girls of Uzbek nationalityMaterials and Methods: We conducted a comparative analysis of the effect of 21-CYP mutations on the clinical symptoms of pathology and the hormonal status of girls with PA. In this regard, the girls were divided into 2 groups: group 1 consisted of 36 girls in whom the 21-CYP mutation was not identified, grou...