hrp0098p3-210 | Pituitary, Neuroendocrinology and Puberty | ESPE2024

Hypergonadotropic hypogonadism in a girl after bone marrow transplantation from a male unrelated donor.

Shuperliska Elizabeta , Shukarova-Angelovska Elena , Krstevska-Kostantinova Marina , Jancevska Aleksandra , Ivanova Daniela

Background: Primary hypogonadism in females is characterized by inadequate ovarian function, resulting in insufficient or absent production of estrogens. This case report aims to present a rare case of primary amenorrhea in a female child where bone marrow transplantation (BMT) was performed due to the beta-thalassemia.Case presentation: A 14-year-old girl approached the endocrinology department for evaluation due to del...

hrp0098p3-253 | Thyroid | ESPE2024

Growth hormone deficiency in patients with late detected Hashimoto thyroiditis-how long to wait for treatment

Sukarova-Angelovska Elena , Shuperliska Elizabeta , Krstevska-Konstantinova Marina , Janchevska Aleksandra , Sapundjija-Karadjoska Felina

Background: Chronic autoimmune thyroiditis (AT) is a leading cause for acquired primary hypothyroidism in children. The prevalence of the AT in pediatric age is lower than in adults - approximately 2%. Familial predisposition is well established, however exact pathophysiologic mechanism is still not known. Since the first signs of Hashimoto thyroiditis are nonspecific and challenging to recognize, also the disease is not associated with pediatric age, the diag...