hrp0082p2-d3-505 | Perinatal and Neonatal Endocrinology | ESPE2014

Random Serial Cortisol Levels in Neonates: Does it Reduce Synacthen Testing?

Pye Susannah , Smith Zoe , Amin Rakesh

Background: Diagnosis of adrenal insufficiency in the neonatal period is most accurately diagnosed with a short Synacthen test. Some tertiary endocrinology centres advocate random serial cortisol measurements over a 3-h period; a normal cortisol reading during such a test would negate the need for a Synacthen test.Objective and hypotheses: Our aim is to assess whether serial cortisol level readings accurately identifies neonates with normal adrenal funct...