hrp0097lb17 | Late Breaking | ESPE2023
Vlachopapadopoulou Elpis
, Thornton Paul
, Hofman Paul
, Nadgir Ulhas
, Saenger Paul
, Malievskiy Oleg
, Aghajanova Elena
, Korpal-Szczyrska Maria
, Mao Meng
, Abdelrahman Sohair
, Komirenko Allison
, Shu Aimee
, Maniatis Aristides
Introduction: Lonapegsomatropin (SKYTROFA, TransCon hGH), a prodrug of somatropin administered once-weekly, is approved for the treatment of pediatric growth hormone deficiency (GHD) by the Food and Drug Administration and European Commission. In the pivotal 52-week phase 3 heiGHt trial and 26-week fliGHt trial (enrolled treatment-naïve and treatment-experienced participants, respectively), lonapegsomatropin demonstrated safety and efficacy in children wi...