ESPE Abstracts

Background: The hypothalamic-pituitary-adrenal (HPA) axis is vital for stress response and homeostasis. Central adrenal insufficiency (CAI) results from inadequate adrenocorticotropin (ACTH) secretion due to hypothalamic or pituitary disorders, leading to insufficient adrenal cortisol production. CAI manifests in nonspecific symptoms and can cause life-threatening adrenal crises. Diagnostic delays are common due to the nonspecific symptoms, making accurate and...