hrp0084p2-201 | Adrenals | ESPE2015

Improved Linear Growth in Patients with Classical Congenital Adrenal Hyperplasia

Roma Silvia , Bizzarri Carla , Scire Giuseppe , Spadoni Gian Luigi , Cappa Marco , Maggioli Chiara

Background: Poor linear growth is still one of the main concerns in children with congenital adrenal hyperplasia (CAH). An impairment of linear growth, adversely affecting final height, has been related both to overtreatment with glucocorticoid replacement therapy and to poor control of adrenal androgen levels.Objective and hypotheses: To define factors that influence linear growth and final height in patients with classical CAH.Me...

hrp0082p2-d1-517 | Pituitary | ESPE2014

Could Brain MRI Replace GH Stimulation Tests in the Work-Up of GH Deficiency in the First Years of Life?

Pedicelli Stefania , Scire Giuseppe , Pampanini Valentina , Gubinelli Jessica , Spadoni Gian Luigi , Bitti Maria Luisa Manca , Cappa Marco , Boscherini Brunetto , Cianfarani Stefano

Background: Currently, the diagnosis of GH deficiency (GHD) in infants and young children is based on the assessment of GH serum levels either during hypoglycaemia or after pharmacological stimulation tests. However, GH cut-off values have not been standardized and provocative tests may be unsafe in this age range.Objective and hypotheses: Brain MRI may replace GH measurements in diagnosing GHD in infancy and young childhood.Method...