hrp0086p2-p974 | Thyroid P2 | ESPE2016

Severe Growth Retardation and Hypothyroidism due to Hashimoto’s Thyroidits

Krstevska-Konstantinova Marina , Stamatova Ana , Gucev Zoran

Background: Hashimoto’s thyroiditis is a common autoimmune disease in pubertal and adolescent girls. In the past years the incidence of this autoimmune disease of the thyroid gland has increased.Objective and hypotheses: We present a 12.5 year old girl who had her first visit at our Pediatric Endocrinology Department at the age of 10 years due to short stature and clinical signs of hypothyroidism. Her height was – 3SD SDS and her BMI was 12.7. ...

hrp0089p3-p312 | Pituitary, Neuroendocrinology and Puberty P3 | ESPE2018

Premature Thelarche Followed by Acute Lymphoblastic Leukemia in a 1.5 Year Old Girl

Krstevska-Konstantinova Marina , Stamatova Ana , Kuzevska-Maneva Konstandina , Kocheva Svetlana , Conevska Biljana , Martinova Kata , Jovanovska Aleksandra

Introduction: Premature thelarche is considered a benign condition of breast development in prepubertal girls. It usually resolves after a certain period of time.Materials and methods: A 1.5 year old girl was referred to the pediatric Endocrinology department due to breast development which appeared two months prior to the visit.Results: Upon clinical examination the patient had Tanner breast stage M2-3 bilaterally, but otherwise a...

hrp0086p2-p677 | Growth P2 | ESPE2016

LHX-4 Gene Mutation in a Boy with Hypopituitarism and Severe Congenital Myopathy

Gucev Zoran , Tasic Velibor , Plasevska-Karanfilska Dijana , Stamatova Ana , Laban Nevenka , Polenakovic Momir

Background: LHX4 mutations are rare in combined pituitary hormone deficiency, and even rarer in isolated GHD.Objective and hypotheses: We describe a 14 years old boy who was referred for investigation of short stature.Methods and Results: Short stature, convergent strabismus, nystagmus was present. At the age of 5 years his gait was unstable. A progressive myopathy ensued. Tests of pituitary reserve showed partial IGHD (8....

hrp0089p3-p313 | Pituitary, Neuroendocrinology and Puberty P3 | ESPE2018

Two Cases of Non-syndromic Congenital Unilateral Hypoplasia in One Family

Stamatova Ana , Kuzevska-Maneva Konstandina , Sukareva-Angelovska Elena , Gucev Zoran , Tasic Velibor , Hofele Julija , Krstevska-Konstantinova Marina

Introduction: Micromastia or breast hypoplasia is a condition which is described as postpubertal underdevelopment of a woman’s mammary tissue. Breast hypoplasia may be congenital or acquired. The defect can be isolated or associated with other pathology, including syndromes and chest wall anomalies, it can also be unilateral or bilateral. Unilateral congenital breast hypoplasia is a rare anomaly of breast development, whose incidence is unclear.Meth...

hrp0092p3-284 | Late Breaking Abstracts | ESPE2019

Demographic, clinical and Biochemical Characteristics of Pediatric Obesity: Interim Analysis of a Larger Prospective Study

Tankoska Maja , Jakimovski Dejan , Murtezani Avdi , Stamatova Ana , Maneva Elita , Shukareva-Angelovska Elena , Gjurkova-Angelovska Beti , Koceva Svetlana , Krstevska-Konstantinova Marina , Kuzevska-Maneva Konstandina

Background: Pediatric obesity is the most common nutritional disorder that affects more than a third of the young population and predisposed individuals to greater future morbidity and mortality. Therefore, rising obesity epidemics becomes is becoming one the most important healthcare problems.Methods: In the period of 2017-2018, 62 consecutive pediatric patients referred to the University Pediatric clinic were recruited...