ESPE Abstracts

Background: Hypoglycaemia is a common critical condition in paediatric emergencies, with diverse aetiologies including metabolic disorders and endocrine dysfunctions. Adrenal insufficiency is a life-threatening cause, that requires prompt diagnosis and intervention. This case study presents a rare incidence of hypoglycaemia secondary to adrenal failure in a paediatric patient with Kearns-Sayre Syndrome (KSS), a mitochondrial disorder affecting multiple systems...

Presentation: A 15-year-old girl presented to Paediatric A&E with lethargy, polyuria, polydipsia and blurred vision. Initial blood gas showed a pH of 7.28, blood glucose unrecordable and ketones of 4mmol/L. The patient was started on IV fluids and insulin, according to the diabetic ketoacidosis (DKA) protocol, and a new diagnosis of type 1 diabetes mellitus was made.Investigations: Finger-prick capillary sampling pro...

Background: There has been a secular increase in Precocious puberty in recent years. We have also seen an increase in referrals and confirmed cases of precocious puberty in our clinics. The suspected cased underwent a Gonadotrophin Releasing Hormone (GnRH) test (GnRH) The initiation of therapy is discussed with tertiary endocrinologist colleagues, but the treatment has been delivered locally. We have recently discussed with colleagues from pharmacy aspects rel...