hrp0084p2-173 | Adrenals | ESPE2015

Normal Ranges of Basal and Glucagon-Stimulated Free Cortisol in Children

Davidov Anita Schachter , Eyal Ori , Anat Anat Becker , Oren Asaf , Stern Naftali , Limor Rona , Weintrob Naomi

Background: Standard assays for serum cortisol measurements determine total cortisol (TC) concentrations but not the unbound biologically active serum free cortisol (sFC). Measurement of TC would be greatly influenced by alteration in cortisol-binding globulin (CBG) concentrations. It is, therefore, important to determine sFC levels when CBG levels are either decreased or increased.Objective and hypotheses: To determine basal and glucagon-stimulated sFC ...