hrp0084p3-1001 | Gonads | ESPE2015
Miyoshi Yoko
, Yasuda Kie
, Miyamura Takako
, Miyashita Emiko
, Hashii Yoshiko
, Ozono Keiichi
Background: Gonadal dysfunction is one of the major endocrinological late effects among cancer survivors. Chemotherapeutic agents and radiation are so gonadotoxic that ovarian reserve diminishes. Measurement of anti-müllerian hormone (AMH) concentration is useful as a marker of ovarian reserve or gonadal deficiency in female childhood cancer survivors (CCSs), particularly among patients without high gonadotropin levels.Objective and hypotheses: The ...