hrp0095lb19 | Late Breaking | ESPE2022
, GM Arets Hubertus
, K van der Ent Cornelis
, M van Santen Hanneke
, J van der Kamp Hetty
Background: Rapid BMI increase in early childhood was found to be a contributing factor for impaired final height in boys with Cystic Fibrosis (CF). This may be explained by early adrenarche triggering an accelerated bone maturation resulting in a compromised growth spurt during puberty, comparable to children with SGA. In healthy Dutch boys, adrenarche starts from the age of 9 years with DHEAS ≥ 1 µmol/L. In Dutch girls, the onset of adrenarche is fr...