hrp0098rfc10.5 | Multisystem Endocrine Disorders | ESPE2024

GAD-65 antibody positive autoimmune encephalitis with type III autoimmune polyendocrine syndrome: a rare pediatric case report

Xie Rongrong , Chen Linqi , Wu Haiying , Zhang Dandan , Chen Xiuli , Wang Fengyun , Sun Hui , Cheng Ting , Wang Manli , Zhang Liya , Tang Jihong

Antibodies to GAD-65 have been associated to type 1 diabetes and different neurological disorders, however these diseases rarely occur concurrently. In this report, we present a rare pediatric case of concurrent GAD-65 antibody positive autoimmune encephalitis and type III autoimmune polyendocrine syndrome (coexisting with autoimmune thyroid disease and type 1 DM). A 7-year-old Chinese female patient presented with a 2-month history of idiopathic seizures. Laboratory tests rev...