hrp0098p2-257 | Sex Differentiation, Gonads and Gynaecology, and Sex Endocrinology | ESPE2024

Clinical and Laboratory Characteristics of Children with Congenital Adrenal Hyperplasia (CAH): A Comparative Study of Hypertensive and Normotensive Patients

Elsayed Shayma , Tawfeek Soliman Ashraf , Elawwa Ahmed , Alaa ElDin Thabet Mohamed , Marzouk Iman , Elneely Dalia , Diab Dina

Background: Hypertension is a recognized complication in children with Congenital Adrenal Hyperplasia (CAH) due to 21-hydroxylase deficiency, treated with glucocorticoids and mineralocorticoids. This study aims to compare the clinical and laboratory characteristics of children with CAH who developed hypertension with those who maintained normal blood pressure (BP) over a treatment course.Methods: This retrospective cohor...

hrp0098p3-235 | Sex Differentiation, Gonads and Gynaecology, and Sex Endocrinology | ESPE2024

Comparative Analysis of Clinical Presentation and Hormonal Profiles in Egyptian Pediatric Patients with 11-Beta-Hydroxylase and 21-Hydroxylase Deficient Congenital Adrenal Hyperplasia

Diab Dina , Alaa El-Din Thabet Mohammed , Mohamed Marzouq Iman , Elneely Dalia , Tawfeek Soliman Ashraf , Elawwa Ahmed , Elsayed Shaymaa

Introduction: Congenital Adrenal Hyperplasia (CAH) encompasses a spectrum of genetic disorders resulting from enzyme deficiencies that impair adrenal steroidogenesis. The most common forms are due to 21-hydroxylase and 11-beta-hydroxylase deficiencies, each presenting with distinct clinical and hormonal profiles.Aim: This study aims to compare the clinical presentations and laboratory findings in Egyptian pediatric patie...