hrp0098rfc15.2 | Late Breaking | ESPE2024

Study on effects of poly- and perfluoroalkyl substances on hormones in girls with central precocious puberty

Li Yan , Xing Yanan , Yin Xiaoqin , Yang Jiaoru , Zang Shaolian , Dong Ting , Pan Yitao , Dai Jiayin , Li Pin

Background: The pathogenesis of central precocious puberty (CPP) is complex, and exposure to environmental endocrine disruptors leading to CPP deserves attention. Poly- and perfluoroalkyl substances (PFASs) can interfere with sexual development, but there are few reports of their effects on sexual hormones and other hormones in CPP girls.Objective: To explore the levels of PFASs in CPP girls and healthy control girls age...