hrp0098p1-219 | Bone, Growth Plate and Mineral Metabolism 3 | ESPE2024

Prospective longitudinal assessment of bone mineral density, circulating markers of bone turnover and changes in body composition in children and adolescents treated for acute lymphoblastic leukemia

Molinari Silvia , Laura Nicolosi Maria , Capitoli Giulia , Tondelli Daniele , Corbetta Sabrina , Vai Silvia , Radaelli Silvia , Biondi Andrea , Adriana Cristina Balduzzi , Sala Alessandra , Cattoni Alessandro

Background: Acute lymphoblastic leukemia (ALL) is the most frequently reported cancer in paediatrics. Reduced bone mineral density (BMD) and increased risk of fractures have been well-documented in this population, but long-term longitudinal trendlines of BMD and data about the impact of bone turnover markers are still scarce. Additionally, changes in body composition have to be furtherly analysed among childhood ALL survivors.St...

hrp0098p1-176 | Pituitary, Neuroendocrinology and Puberty 2 | ESPE2024

Pelvic ultrasound and pubertal attainment in girls with sexual precocity: the pivotal role of uterine volume in predicting the timing of menarche

Cattoni Alessandro , Russo Gianni , Capitoli Giulia , Rodari Giulia , Laura Nicolosi Maria , Molinari Silvia , Tondelli Daniele , Pelliccia Ciretta , Radaelli Silvia , Arosio Andrea , Fondata Katia , Tattesi Giulia , Passoni Paolo , Boneschi Annalisa , Giavoli Claudi , Laura Carla Meroni Silvia , Rita Stancampiano Marianna , Garuti Elda , Biondi Andrea , Balduzzi Adriana , Bizzarri Carla

Introduction: Among girls assessed for pubertal precocity, pelvic ultrasound (pUS) may represent a pivotal tool to predict the time expected to elapse between sonographic assessment and the onset of menarche (TUS-M). Accordingly, the present analysis is meant to define the statistical relationship between sonographic parameters and TUS-M, in order to identify the most reliable predictor of the timing of menarche.<st...