hrp0095p1-26 | Bone, Growth Plate and Mineral Metabolism | ESPE2022

Outcomes of four patients with osteonecrosis after one-year pamidronate treatment

Yüksek Acinikli Kübra , Besci Özge , Yaşar Elif , Tüfekçi Özlem , Karadağ Zehra , Yıldız Gizem , Torun Rüya , Akın Kağızmanlı Gözde , Torun Bayram Meral , Yılmaz Şebnem , Güleryüz Handan , Abacı Ayhan , Böber Ece , Demir Korcan

Background: Osteonecrosis (ON) is bone death caused by inadequate blood supply resulting in demineralization and trabecular thinning and, subsequently, mechanical failure. Although the pathophysiology of ON is not fully understood, the use of high-dose glucocorticoid (GC) is one of the triggers. Furthermore, its optimal management remains uncertain. The use of bisphosphonates (BP) for the treatment of ON has been reported, however, data on outcomes are limited...