hrp0097p1-101 | GH and IGFs | ESPE2023
Vliegenthart Joeri
, Wit J.M.
, Bakker B.
, Boot A.M.
, de Bruin C.
, Finken M.J.J.
, van der Heyden J.C.
, Houdijk E.C.A.M.
, van der Kamp H.J.
, van Mil E.G.A.H.
, Reedijk A.M.J.
, Sas T.C.J.
, Schott D.A.
, van Setten P.
, Straetemans S.
, van Tellingen V.
, Touwslager R.N.H.
, van Trotsenburg A.S.P
, Voorhoeve P.G.
, van der Kaay D.C.M.
Background: The majority of children diagnosed with idiopathic isolated growth hormone deficiency (IIGHD) show a normal growth hormone (GH) secretion (assessed by GH stimulation tests) when retested at near adult height (NAH). It appears plausible that if normal stimulated GH secretion is observed in mid-puberty, continuing recombinant human GH (rhGH) treatment may only have a minor effect on NAH. The effect on NAH has never been investigated in a prospective ...