hrp0097fc2.3 | Bone, Growth Plate and Mineral Metabolism | ESPE2023
V Zhukouskaya Volha
, Ertl Diana-Alexandra
, Berkenou Jugurtha
, Audrain Christelle
, Bardet Claire
, Rothenbuhler Anya
, Linglart Agnes
Background/aim: Hyperparathyroidism (HPHT) is a common feature in patients with X-linked hypophosphatemia (XLH) especially when treated with vitamin D analogues and phosphate supplements. Although the exact mechanism is not clear, it is assumed that phosphate supplements taken chronically stimulate parathyroid hormone (PTH) secretion. We prospectively assessed the effect of a novel pathogenetic treatment anti-FGF23 (burosumab) on PTH levels in children with XL...