hrp0082fc3.2 | Diabetes | ESPE2014

HbA1c Level as a Predictive Marker of Progression to Clinical Diabetes

Petruzelkova Lenka , Vcelakova Jana , Labikova Jana , Lebl Jan , Kolouskova Stanislava

Background: It has been shown that a proportion of relatives with multiple islet auto antibodies do not develop diabetes for many years, indicating that a more accurate marker of advanced insulitis is needed.Objective and Hypotheses: We evaluated whether the level of HbA1c can discriminate children at risk of T1D onset in a cohort of auto antibody positive relatives.Method: A total of 74 subjects <18 years of age who were parti...