hrp0082fc14.1 | Puberty | ESPE2014

Brain Structure and Function in Gender Dysphoric Adolescents

Hannema Sabine , Schagen Sebastian , Hoekzema Elseline , Kreukels Baudewijntje , Veltman Dick , Cohen-Kettenis Peggy , Bakker Julie , Delemarre-van de Waal Henriette

Background: Gender dysphoria is characterised by an incongruency between the perceived gender identity and the biological sex. The cause of gender dysphoria is unclear and environmental as well as genetic factors may be important. It is well known that during sexual differentiation sex steroids control not only the differentiation of the internal and external genitalia but also the sexual differentiation of the brain. Structural as well as functional differences have been show...