ESPE Abstracts

Background: Fetal growth is the fastest of all periods of growth in human life, mainly due to cellular hypertrophy and proliferation. It was recently discovered that the metabolic and mitogenic effects of Insulin are mediated by two Insulin Receptors (IR) isoforms, IR-A and IR-B. High expression of IR-A indicates proliferation and differentiation whereas IR-B indicates metabolic dominance.Objective and hypotheses: The aim of the study was to examin the e...