hrp0098p1-211 | Adrenals and HPA Axis 3 | ESPE2024

Non tumoral ACTH-Independent Cushing Syndrome in Pediatric Patients: A Retrospective Observational Cohort Study

Hassan Myriam , Samara-Boustani Dinane , Besançon Alix , Rothenbuhler Anya , Storey Caroline , Pinto Graziella , Stoupa Athanasia , Nicolino Marc , Gonzalez-Briceno Laura , Nguyen Quoc Adrien , Vermillac Gaelle , Rovani Sibylle , Flechtner Isabelle , Thalassinos Caroline , Dassa Yamina , Beatriz Arrom Branas Maria , Viaud Magali , Beltrand Jacques , Ribault Virginie , Martinerie Laetitia , Linglart Agnès , Bertherat Jerôme , Blanc Thomas , Polak Michel , Kariyawasam Dulanjalee

Purpose: ACTH-independent bilateral adrenal hyperplasia is a rare cause of pediatric Cushing's syndrome (CS). Our objective was to describe the features of pediatric ACTH-independent CS and to compare groups defined by etiology.Methods: We conducted a retrospective observational study of patients aged 0–18 years at management in 1992–2022 for ACTH-independent CS in any of three Paris university pediatric...