hrp0098s2.1 | Bone and Mineral Disorders: Recent Developments | ESPE2024

Phosphate sensing in normal physiology and disease

Wagner Carsten

Inorganic phosphate (Pi) is an essential mineral required for the formation of bone, cell membranes, energy metabolism, storage and transmission of genetic information, cellular signaling events, or acid-base buffering. Diet provides phosphate in various forms ranging from plant-derived phytates with low bioavailability to animal proteins and inorganic phosphate salt with high and very high bioavailability, respectively. Since intestinal absorption of bioavailable phosphate is...