hrp0086wg3.2 | ESPE Turner Syndrome Working Group (TS) | ESPE2016

Skeletal Disproportion In Turner Syndrome

Wong Jarod Sze Choong

Short stature and skeletal disproportion is recognised in individuals with Turner Syndrome, with several studies demonstrating disproportionately lower leg length compared to sitting height. The skeletal disproportion is thought to at least,in part, to be due to the short stature homeobox containing gene (SHOX) abnormality. Whilst all girls with short stature deserve investigation to rule out Turner Syndrome, the identification of a short pre-pubertal girl with disproportionat...

hrp0084s10.3 | Growth plate in chronic diseases | ESPE2015

Bone Health in Chronic Disease

Wong Jarod S C

Abnormal bone development is commonly seen in children with chronic disease. However, fragility fractures in the young individual may be less common compared to older adults, which may be due to under recognition. The underlying chronic condition and medication can impact on bone turnover, modelling, bone mineral homeostasis, growth, pubertal development and muscle mass. The diagnosis and management of osteoporosis in children and adolescents with chronic disease remains conte...

hrp0095p2-7 | Adrenals and HPA Axis | ESPE2022

Suboptimal cortisol response on ITT and subsequent adrenal insufficiency

Boyle Roisin , Sanderson Jennifer , Purton Daniel , Angela Lucas-Herald , McNeilly Jane , Mason Avril , Wong Jarod , Guftar M Shaikh , Ahmed Faisal

Background: Insulin Tolerance tests (ITT) have long been considered the gold standard for dynamic function testing of the hypothalamo-pituitary-adrenal (HPA) axis. Sub-optimal cortisol responses during an ITT in children may be found in children during ITT without a previous clinical suspicion of Adrenal insufficiency (AI). It is not clear what the clinical significance of this is and whether all of these children require formal synacthen testing.<p class=...