hrp0084p1-62 | DSD | ESPE2015
Cools Martine
, Wolffenbuttel Katja P
, Kaprova Jana
, Mendonca Berenice B
, Drop Sten LS
, Hersmus Remko
, Stoop Hans
, Gillis Ad JM
, Costa Elaine MF
, Domenice Soraiah
, Wunsch Lutsz
, Quigley Charmian
, Arlt Wiebke
, T'Sjoen Guy
, Looijenga Leendert HJ
Background: Gonadectomy is generally postponed until early adulthood in complete androgen insensitivity syndrome (CAIS) and close surveillance of gonads in situ proposed in males with partial AIS (PAIS). Delaying gonadectomy further is controversial given the lack of data regarding germ cell cancer (GCC) development in adulthood and the absence of biomarkers for noninvasive GCC screening.Aims and objectives: To study the prevalence of invasive G...