hrp0098p2-343 | Late Breaking | ESPE2024

Reshaping of the chromatin landscape and angiogenic process in umbilical vein endothelial cells of small for gestational newborns

Yan Lingling , Wang Chunlin

The condition of being small for gestational age (SGA) poses significant risks to both infant development delay and chronic non-communicable diseases in adultood, especially cardiovascular diseases. Despite the known association between SGA and endothelial dysfunction, the precise pathogenic genes and underlying mechanisms driving this pathology have remained elusive. In this study, we conducted a comprehensive evaluation of endothelial dysfunction in SGA by their increased an...