hrp0098p3-275 | Late Breaking | ESPE2024

Effects of gonadotropin-releasing hormone analogue (GnRHa) combined with recombinant growth hormone (rhGH) on growth of girls with central precocious puberty or early and fast puberty

Qiao Yu , Li Guimei

Background: Girls diagnosed with central precocious puberty (CPP) or early and fast puberty (EFP) tend to exhibit temporarily rapid acceleration in growth due to increased sex hormone production or exposure, leading to premature closure of the growth plate and a shorter final adult height (FAH). Rapid progression of the secondary sexual characteristics in children can also cause poor social adaptability, psychological stress, and emotional disorders. CPP/EFP c...