hrp0098p2-266 | Sex Differentiation, Gonads and Gynaecology, and Sex Endocrinology | ESPE2024

Outcome of antenatal treatment in congenital adrenal hyperplasia due to 21 hydroxylase-deficiency in Algeria

Ouarezki Yasmina , Cherfi Nadia , Abbas Wassila , Mimouni Leila , Djermane Adel , Mohammedi Kahina , Tardy Veronique , Menassa Rita , Roucher Florence , Ibsaine Ouardia , Bouzerar Zahir , Maouche Hachemi , Zeggane Houria , Ladjouze Asmahane

Introduction: 21-hydroxylase deficiency (21-OHD) is the most common cause of female virilisation at birth and carries heavy psychosocial consequences. Early antenatal treatment with dexamethasone is successful in avoiding severe virilisation, thus reducing the need for surgery and improving psychological outcome.Objectives: To evaluate the feasibility and effectiveness of antenatal treatment in 21-OHD in a resource-limit...