hrp0095p1-36 | Diabetes and Insulin | ESPE2022

Human umbilical cord derived mesenchymal stem cells alleviate T1DM model via TGFBI-mediated T cells proliferation

Wu Chushan , Xu Tingting , Li Lu , zheng Rongxiu

Type 1 diabetes mellitus is autoimmune T cells mediated destruction of β-cells. Mesenchymal stem cells (MSCs) are considered a promising treatment for T1DM due to the strong immunosuppressive and regenerative capacity. However, the comprehensive mechanism is still unclear. Our previous study indicated that the transforming growth factor beta-induced gene (TGFBI) is highly expressed in human umbilical cord derived mesenchymal stem cells (hUC-MSCs), which is also implicated...

hrp0095p1-394 | Thyroid | ESPE2022

Analysis on the influencing factors of neonatal serum FT3, FT4 and TSH

Zhang Cong , Zheng Rongxiu , Ma Shifeng , Wu Chushan , Liu Xiaoxiao , Cheng Siqi , Zhao Yue , Jiang Haiyan

Background: With the increasing survival rate of extremely premature infants, neonatal thyroid dysfunction is more frequently observed clinically. Despite the guidelines, the timing of screening for neonatal thyroid function remains controversial, especially for premature infants. At present, there is no unified standard for serum FT3, FT4 and TSH levels of newborns of different gestational ages and postnatal days.Objective:</str...