hrp0082p2-d3-393 | Fat Metabolism & Obesity (2) | ESPE2014

Comparison of FMDXA and FMBIA in Obese Adolescents

Ziegler Julian , Schweizer Roland , Binder Gerhard

Background: Determining fat mass (FM) using methods of body composition analysis is useful in diagnosis and treatment of obese adolescents who undergo life style intervention. The use of dual-energy X-ray absorption (DXA) is time-consuming, potentially harmful and expensive. Alternative methods for accurately estimating FM are needed.Objective and hypotheses: We evaluated single-frequency arm-to-leg bioelectrical impedance analysis at 50 kHz (sf-BIA) in ...

hrp0084p1-79 | Growth Hormone | ESPE2015

Decrease of Jumping Power in Adolescents with Severe GHD After Stop of GH-Therapy

Schweizer Roland , Ziegler Julian , Binder Gerhard

Background: Recently we demonstrated that male adolescents with severe GHD (sGHD) had a significant decrease of lean body mass and increase in fat mass after stop of GH-therapy. The functional consequence of this observation is unknown.Objective and hypotheses: The aim was to study the changes in parameters of jumping mechanography in adolescents with GHD in the transition period (end of growth) after stop of GH-therapy.Patients an...

hrp0084p2-423 | GH & IGF | ESPE2015

The Accuracy of Bioelectrical Impedance Analysis to Detect the Body Composition Changes in Adolescents with Severe GHD During Transition

Ziegler Julian , Schweizer Roland , Binder Gerhard

Background: Male adolescents with severe GH deficiency show both loss of lean body mass (LBM) and gain of fat free mass (FFM) when off GH treatment. We recently showed that determining gain of FFM and loss of LBM by dual-energy x-ray absorption (DXA) is helpful in the diagnosis of severe GHD during transition as these body composition changes are correlated to the GH-peak of the arginine-GHRH-re-test.Objective and hypotheses: We wanted to explore if the ...

hrp0082p2-d2-433 | Growth Hormone (1) | ESPE2014

Comparison of Measured Lean Body Mass (LBMDXA) and Estimated LBMBIA in Children with GH Deficiency

Schweizer Roland , Ziegler Julian , Frank Laura , Binder Gerhard

Background: Long standing GH deficiency (GHD) causes loss of muscle mass. DXA enables the measurement of LBMDXA but is accompanied with a potentially harmful X-ray exposition. BIA measures the electric resistance of the body which correlates with LBM. A comparison of both methods in children with GHD has not been performed yet.Aim: Calculation of a regression formula for LBM using resistance and anthropometry based on LBMDXA in chil...

hrp0097p1-240 | Diabetes and Insulin | ESPE2023

Age differences in the distribution of diabetes-specific antibodies in children and adolescents with type 1 diabetes mellitus

Schweizer Roland , Mayer David , Bung Julia , Liebrich Franziska , Neu Andreas , Ziegler Julian

Background: The assignment to type 1 diabetes mellitus (T1DM) can be confirmed by the determination of diabetes-specific autoantibodies. Five different antibodies can be determined. The determination of several antibodies is more expensive than the determination of a single antibody. In times of scarce resources, the sequential determination of antibodies could save costs. The aim of this study was to determine the frequency of antibodies and their age and gen...

hrp0095p1-444 | Diabetes and Insulin | ESPE2022

Influence of Family Status and Living Circumstances on Metabolic Control in Patients with Type 1 Diabetes

Schweizer Roland , Friz Silas , Hayn Clara , Lösch-Binder Martina , Uber Julia , Ziegler Julian , Liebrich Frankziska , Neu Andreas

Object and Aim: The quality of metabolism in type 1 diabetes depends on different external factors, e.g. the circumstances of living of a patient. We investigated how far the family status, living situation or own children have influence on metabolic control in patients who were transferred to adult care after long-term care in pediatric diabetology.Patients and Methods: From 1998 until 2019 we annually sent a questionna...

hrp0089p1-p077 | Diabetes & Insulin P1 | ESPE2018

Additional Insulin is Necessary to Prevent Rise in Blood Glucose after Fat-protein-rich Meals in Type 1 Diabetes

Schweizer Roland , Herrlich Susann , Losch-Binder Martina , Glokler Michaela , Heimgartner Magdalena , Liebrich Franziska , Meszner Katja , Muckenhaupt Tina , Schneider Angelika , Ziegler Julian , Neu Andreas

Background: High amounts of protein in meals increase blood glucose in patients with type 1 diabetes. Fat delays the increase of blood glucose. Till now we do not know the amount of insulin necessary to prevent the increase of blood glucose after a fat and protein rich meal (FPRM).Aim: To find the Insulin dosage to normalize glucose level after a FPRM.Patients: Sixteen patients with type 1 diabetes (mean±SD; Age 19.7±2.7 ...