hrp0089p1-p165 | Growth & Syndromes P1 | ESPE2018
, Laemmer Constance
, Woelfle Joachim
, Goihlke Bettina
Context: Prader-Willi syndrome (PWS) is a multisystemic complex genetic disorder. Individuals with PWS are at risk to develop sleep-disordered breathing, including obstructive and central sleep apnea syndromes. PWS patients commonly receive Growth hormone (GH) treatment. Concerns have been raised following reports of sudden death shortly after GH initiation. During recent years GH treatment was increasingly initiated earlier commencing treatment already during the first...