hrp0098p1-269 | Growth and Syndromes 4 | ESPE2024

Effect of treatment with Isotretinoin on early bone maturation: A Case Report

Scheidemantel Aline , Eduardo Cruvinel Pinto Luís , Junqueira Soares Gabriel , de Lima Carlesso Gabriela , Ricardo Azevedo Silva João , da Silva Almeida Karina , Cardoso-Demartini Adriane

Introduction: Isotretinoin is used for treatment of dermatological diseases, such as severe acne. It’s also recommended for treatment of high-risk neuroblastoma and pediatric medulloblastoma, but in these cases higher doses are necessary.Case report: A 12-year-old male patient with poorly differentiated embryonal origin carcinoma in the posterior fossa and implants in the neuroaxis. Next-generation sequencing genet...