hrp0098rfc15.3 | Late Breaking | ESPE2024

The different faces of acquired hypothalamic dysfunction.

M. van Santen Hanneke , van Roessel Ichelle , Hulsmann Sanne

Background: Acquired hypothalamic dysfunction (HD) in children following suprasellar brain tumor treatment may be caused by the tumor or its treatment (neurosurgery, radiotherapy). Rapid weight gain, obesity and pituitary dysfunction are readily recognized as symptoms of HD, however HD knows other signs and symptoms such as hypothermia, adipsia and behavioral problems. In our clinical experience, signs and symptoms of HD may differ per tumor type and the treat...