hrp0098fc11.6 | Fat, Metabolism and Obesity 2 | ESPE2024

Poly- and Perfluoroalkyl substances (PFAS) levels and breastfeeding have opposite associations with growth and body composition at age 3 years

van Beijsterveldt Inge , Dorrepaal Demi , van Zelst Bertrand , van den Berg Sjoerd , Hokken-Koelega Anita

Background and aims: Poly- and perfluoroalkyl substances (PFAS) are non-degradable, man-made-chemicals. PFAS are considered to be ‘Endocrine Disrupting Chemicals’ (EDCs), a group of chemicals which have been reported to interfere with endocrine processes and cause adverse effects on perinatal, neurodevelopmental, metabolic and reproductive outcomes. Especially when exposure occurs during susceptible periods of human development, such as early life....