hrp0097p2-1 | Multisystem Endocrine Disorders | ESPE2023

Prevalence of Malnutrition and Underweight in Children and Adolescents with Beta-Thalassemia Major (BTM)

Soliman Ashraf , Yassin Mohamed , Alyafei Fawzia , Ahmed Shayma , Alaaraj Nada , Soliman Nada

Introduction: Blood transfusion and iron chelation are conventional treatments for β-thalassemia (BTM). Malnutrition affects the growth, efficacy of treatments, and quality of life in children suffering from BTM.Objective: To evaluate the prevalence of malnutrition (BMI < 3rd centile for age and sex) or BMISDS < -2 in 10 Mediterranean and Middle east countries and the USA in the past 20 years.  <p c...

hrp0097p2-87 | Multisystem Endocrine Disorders | ESPE2023

Undernutrition, abnormal body composition, and impaired linear growth in children and adolescents with Beta-Thalassemia Major: possible contributing factors

Soliman Ashraf , Ahmed Shayma , Alaaraj Nada , Elalaily Rania , Alyafei Fawzia , Hamed Noor , Soliman Nada

Introduction:Blood transfusion and iron chelation are conventional treatments for β-thalassemia (BTM). Malnutrition negatively affects their growth, efficacy of treatments, and quality of life.Objective: To evaluate the nutritional status and linear growth in 10 countries in the past 20 years.Methods: We performed an electronic search in PubMed, Google Scholar, and Web of Scie...

hrp0097p2-280 | Late Breaking | ESPE2023

Prevalence of Childhood Obesity Among Children Visited Paediatric Outpatient Clinics in Oman - A Single Centre Experience

Al-Lawati Osama , Al-Musharafi Ahmed , Al-Ghafri Shahad , Al-Harthi Hamza , Alsaffar Hussain

Introduction: Childhood obesity is a significant public health concern, affecting over 100 million children worldwide, with an overall prevalence of 13%. A previous Omani study in 2012 suggested the prevalence of childhood obesity in Oman was 12.5%.Objectives: This study aims to identify the prevalence of childhood obesity among children under the age of 13 yrs, who visited various pediatric outpatient clinics at Sultan ...

hrp0097p2-291 | Late Breaking | ESPE2023

Early Endocrinopathy in Childhood Cancer Survivors in a Specialized Center in Riyadh

Sultan Alorini , Aldakhil Sadeem , AlKhanbashi Omar , Aljuraibah Fahad , Ahmed Naveed , Essa Mohammad , Babiker Amir

Introduction: Childhood cancer survivors (CCSs) has increased risk of endocrine complications, of which, abnormal growth and hypothyroidism are the commonest. The risk of developing endocrinopathy will vary according to different host factors including type of tumour and factors related to treatment modalities including chemotherapy, radiotherapy, surgery and bone marrow transplantation. we aim to assess the prevalence and associated risk factors of early deve...

hrp0097p2-311 | Late Breaking | ESPE2023

Diagnostic challenges of congenital adrenal hyperplastic (CAH) in a tertiary care hospital of resource limited country

Ayub Aqeela , Sattar Hina , Waris Rehmana , Ayub Hamna , Shahid Gulbin , Shamsher Maria , Ahmed Butt Taeed

Background and objectives: The diagnosis of CAH is a matter of urgent attention as a missed diagnosis can add to mortality due to adrenal insufficiency and inadequate sex of rearing which is psychologically traumatic both for the parents and the child. It is also a matter of grave concern because screening facilities are non-existent in Pakistan along with increase prevalence of intra family marriages thus adding to the increase incidence of this condition. La...

hrp0095fc5.2 | Adrenals and HPA Axis | ESPE2022

Thioredoxin Reductase 2 (TXNRD2) Variant As A Cause Of Micropenis, Undescended Testis And Selective Glucocorticoid Deficiency

Patjamontri Supitcha , Lucas-Herald Angela , McMillan Martin , Prasad Rathi , Metherell Louise , McGowan Ruth , Tobias Edward , Faisal Ahmed S.

Introduction: The molecular aetiology of familial glucocorticoid deficiency (FGD) is very heterogeneous. A recent report of a genetic variant in TXNRD2, the gene encoding thioredoxin reductase Type 2, in a South Asian kindred with FGD suggests that the maintenance of redox balance may be critical for adrenocortical function. We present the second report of an individual from another south Asian family harbouring a different pathological variant in <em...

hrp0095p1-92 | Fetal, Neonatal Endocrinology and Metabolism | ESPE2022

Reference National Standards for Placental Weight in Infants born between the 37th and 43rd weeks of Gestation in Qatar. (A Population-Based Retrospective Data Analysis (n = 80722).

Alyafei Fawzia , Al-qubasi Mai , Soliman Ashraf , Ali Hamdy , Olukade Tawa , Alturk Mohamad , Alaaraj Nada , Hamed Noor , Ahmed Shayma

Introduction: Because of the associations and links between abnormal placental weight and both fetal and maternal disorders, it is important to have the national normal standard for placental weight as a normality reference.Aims: To find out the national placental weight standards for babies born between 37th and 43rd weeks of gestation in all groups of males and females babies born AGA, SGA, and LGA.<p class="abstex...

hrp0095p1-133 | Growth and Syndromes | ESPE2022

Postnatal growth of infants born < 2.5 kg: small for gestational age (SGA) vs appropriate for gestational age (AGA)

Alyafei Fawzia , Soliman Ashraf , AlYousef Doaa , Shaat Mona , Itani Maya , Ali Hamdy , Alaaraj Nada , Hamed Noor , Ahmed Shayma

We studied anthropometric measures (z scores) from birth to 2 years in 115 infants who were born with birth weight <2.5 kg but > 1.5 kg. They were divided into two groups based on Fenton's preterm growth standards at birth. Group 1 (AGA) with weight z score (WAZ) > -2 (n = 100), and group 2 (SGA) with WAZ < -2 (n = 15). Postnatal growth data were evaluated based on the WHO growth standard without correction for prematurity.<p class="abste...

hrp0095p1-527 | Growth and Syndromes | ESPE2022

The Cumulative incidence of SGA, AGA and LGA, Premature, Postmature, and Term birth in infants born between the 33rd weak and the 44th weeks of Gestation in Qatar

Alyafei Fawzia , Soliman Ashraf , Alqubasi Mai , Olukade Tawa , Ali Hamdy , Alturk Mohamed , Alaaraj Nada , Hamed Noor , Ahmed Shayma

Introduction: Prematurity, post-maturity, and significant deviations in birth weight are associated with significant morbidities and mortalities.Aim: The aim of this study was to identify the cumulative incidence (CI) of premature, postmature, and term birth rates additionally to find out the prevalence of SGA, AGA, and LGA using INTERGROWTH-21 st fetal growth standards.Methods: Th...

hrp0095p1-530 | Growth and Syndromes | ESPE2022

Proportions of abnormal growth parameters in extremely low birth weight infants (ELBW) during the first 3 years of life: weight Z score(WAZ), length Z score (LAZ), weight for length Z score (WLZ), and head circumference Z score (HCZ)

Alyafei Fawzia , Soliman Ashraf , Alkhori Fatima , Ali Hamdy , Alaaraj Nada , Hamed Noor , Ahmed shayma , Alhemaidi Noora , Abbasi Saleha

Introduction: This study evaluated the postnatal growth of infants born with extremely low birth weight (ELBW) < 1 kg for 3 years.Method: Anthropometric measures (z scores) from birth, 2,4.6,12,18,24, and 36 months were measured in 87 randomly selected infants who were born with a birth weight below 1 kg (9-2016: 9-2018). Their growth data were compared to standard growth for normal age and sex using WHO growth standa...