ESPE Abstracts

Background: Small gestational age (SGA) is defined by a small size and/or a birth weight <−2 DS/standards for the term of pregnancy. Most of these children catch up to their size in the first 2 years of life. Only 10% of them will stay with a size of <−2 DS. These children may benefit from treatment with GH, which improves their stature prognosis.Objective and hypotheses: Study the final height of children with IUGR have reached adult...

Background: Delayed puberty in girls is evoked at the absence of breast development after the age of 13 years. It is relatively rare and must look contrary to the boy an organic cause.Objective and hypotheses: Search the frequency and aetiology of delayed puberty in girls.Method: This is a retrospective study of patients consulting for delayed puberty and collected in 5 years. The of patients was compared to the number of delayed p...

Background: The thyroid disorders in children and adolescents are varied. They are dominated by frequent malignant tumour lesions and goitres represented by Graves’ disease and Hashimoto’s thyroiditis in adolescence. They are characterized by several clinical forms.Objective and hypotheses: To study the clinical and aetiological characteristics of thyroid disease in children and adolescents.Method: This is a retrospective...

Background: Trisomy 21 is a chromosomal abnormality that predisposes to autoimmune diseases. Among them the thyroid dysfunction is frequently observed.Objective and hypotheses: Study the various thyroid diseases in trisomy 21 patients and their therapeutic management.Method: This is a retrospective study of 50 cases of Down syndrome children with thyroid disease, collected over a period of 9 years (2006–2015). All children und...

Background: The hypothyroidism is defined by an elevated TSH with normal fT4 and the absence of symptoms of hormonal deficiency. In children and adolescents, it is mainly due to chronic thyroiditis or radiotherapy for cervical cancer.Objective and hypotheses: Assess clinical, etiological and evolutionary characteristics of subclinical hypothyroidism in children and adolescents.Method: This is a retrospective and prospect...

Background: Adrenal insufficiency in children is rare and potentially serious because of the risk of acute adrenal insufficiency. This complication is lethal in the absence of prompt and appropriate treatment. Aetiologies are dominated by the genetic causes.Objective and hypotheses: Report diagnostic circumstances,phenotypic forms and causes of adrenal insufficiency in children and adolescents.Method: This is a retrospective study ...

Background: Hormone deficiency no or late treated causes delayed puberty and reduced final height.Objective and hypotheses: Assess the progress of puberty in isolated GH deficient (GHD) patients.Method: 34 patients with GHD in puberty were followed in endocrinology. The average age at diagnosis of GH deficiency was 8±2.4 (7–19) in girls and 9±1.2 (8–18) in boys. The majority of patients received an irregular GH ...

Background: Disorders of sexual differentiation (DSD) at birth is a serious defect often seen in endocrinology. Diagnosis must be early to ask an etiologic diagnosis, choose the sex of rearing and effectively treat the disease.Objective and hypotheses: Search etiologies of sexual ambiguities and clarify the phenotypic characteristics.Method: This is a retrospective study of 180 sexual ambiguities hospitalized. All patients underwen...

Background: The ganglioneuroma (GN) is a benign tumor of the sympathetic nervous system following the sympathogonies that affects children and young adults. This is a rare tumor (7/1 000 000) which can be located along the sympathetic chain from the neck to the pelvis. In 20% of cases, the GN is localized in the adrenal.Objective and hypotheses: Report observations of eight patients with GN.Observations: Eight patients (two boys an...

Background: Achondroplasia is the most common cause of genetic dwarfism with a prevalence of 1/10 000 to 30 000 birth. It is a pathology of dominant inheritance linked to the mutation of the receptor gene growth factor on chromosome 4p16 fibroblastes FGFR3 responsable rhizomelic dwarfism and multiple complications likely to compromise the functional and vital prognosis of patients.Objective and hypotheses: Find the frequency of neurological complications...