ESPE Abstracts

Introduction: Previous studies have demonstrated varying patterns of growth in children with Growth Hormone Deficiency (GHD), particularly in the first two years of life, a period crucial for growth and development. This study aims to compare the early growth patterns, specifically the rate of catch-down growth in the initial months post-birth, of children diagnosed with GHD. By juxtaposing our findings with existing literature, we seek to deepen the understan...

Background: To understand the quality of information that is available in the I-DSD Registry (https://sdmregistries.org/), this study aim ed to understand the extent of information that is available on the phenotype of the external genitalia in males that have been included with a condition associated with a suspected hypogonadal state and DSD.Methods: A total of 3,248 m...

Introduction: Growth hormone therapy is a cornerstone treatment for children with GHD and ISS. Its impact on the hypothalamic-pituitary-thyroid axis, however, has been a subject of ongoing research.Review of Literature:Early Observations (1992-2005): Pirazzoli et al. (1992) and Tang et al. (1997) were among the first to document changes in thyroid function due to ...

Introduction: Hypothyroidism in children leads to growth retardation. However, there is some evidence that recombinant human growth hormone (rhGH) therapy could suppress thyroid function. The actual incidence is controversial, however, with some studies showing a rare and others a high occurrence.Aim and Methods: This study examines the effects of Growth Hormone (GH) therapy on thyroid function, specifically focusing on ...

Diabetic nephropathy is the leading cause of chronic renal failure. Poor metabolic control exposes the patient to multiple chronic complications, the most serious of which is diabetic nephropathy. This complication is the leading cause of chronic renal failure.Aims: the main aimof our work is to assess the frequency of nephropathy in diabetic children and to study the impact of clinical parameters and metabolic control on microalbuminuri...

Introduction: The prevalence of obesity in children and adolescents is increasing globally, prompting investigations into its effects on various health parameters, including thyroid function.Aim of the Review: To elucidate the relationship between obesity and thyroid function in the pediatric population through a review of recent studies.Review Results: Analysis of studies involvin...

Introduction: This study presents a comparative analysis of the efficacy of sex steroid priming in enhancing growth hormone (GH) responses in short stature children undergoing GH stimulation tests.Methods: A randomized study encompassed a cohort of 40 children, divided into two groups: "With Priming" and "Without Priming". The primed group exhibited a higher peak GH response (6.53) compared to the non...

Introduction: Growth hormone (GH) therapy in Turner Syndrome (TS) affects growth and glucose metabolism.Methods: Reviewed studies focused on GH therapy's impact on glucose metabolism in TS, selecting those with clear outcomes and sufficient sample sizes.Results: The effects of GH therapy on glucose metabolism in TS vary, with studies indicating both potential risks and benefit...

Introduction: Precocious puberty, is the development of sexual characteristics occurring before the age of 8 in girls and 9 years in boys, it is a reason for consultation which is becoming frequent, the etiologies are numerous, it Central forms mainly act by early activation of hypothalamic-pituitary-gonadal (HPG) axis which can be idiopathic or secondary to congenital or acquired lesions, rarely the peripheral origin can be the cause.<s...

Introduction: Managing pediatric hypothyroidism with thyroxine therapy is crucial for children's growth and development. This presents a synthesized overview of the relationship between thyroxine therapy and growth outcomes in children with congenital and acquired hypothyroidism.Methods: A literature review from 1987 to 2013 was conducted, selecting studies on thyroxine therapy's effects on linear growth, cogni...