hrp0095mte1 | Pediatric Cushing Disease | ESPE2022

Pediatric Cushing disease

By far, the most common type of CS is due to exogenous causes, i.e. medication-induced CS. Endogenous causes are rare by they are all associated with one form of another of a tumor. We call Cushing Disease (CD) what is caused by pituitary adenomas only. It is common for children with CD to show an increase in rate of weight gain accompanied by a decrease in growth rate (linear height) due to decreased growth hormone secretion. This is often easily detected in growth charts of ...

hrp0095mte3 | The key role of physical activity against the cardiometabolic risk in childhood obesity | ESPE2022

The key role of physical activity against the cardiometabolic risk in childhood obesity

Valerio Giuliana

Children and adolescents with obesity and clustering of cardiometabolic risk factors, such as hypertension, dyslipidemia, and prediabetes are exposed to endothelial damage, vascular and myocardial remodeling, and atherosclerosis. If not adequately treated, these alterations may contribute to early morbility and mortality for adverse cardiovascular events in adulthood. Physical activity (PA) plays an important role in the treatment of obesity and its cardiometabolic comorbiditi...

hrp0095mte5 | Initial evaluation of a suspected difference or disorder of sex development | ESPE2022

Initial evaluation of a suspected difference or disorder of sex development

Ahmed S. Faisal

It is important that any child or adolescent with a suspected difference or disorder of sex development (DSD) is assessed by an experienced clinician with adequate knowledge about the range of conditions associated with DSD. In most cases, the paediatric endocrinologist within this service acts as the first point of contact but involvement of the regional multidisciplinary service is critical. The members of this service should be involved in education and training as well as ...